What is the correct sequence of phases in dermal wound healing?

The correct sequence of phases in dermal wound healing is the inflammatory, migratory, proliferative, and maturation phases.

Initially, the inflammatory phase is critical as it serves to prevent infection and establish a protective barrier around the wound. This is characterized by the presence of immune cells and the release of signaling molecules that initiate the healing process.

Following the inflammatory response, the migratory phase begins, which involves the movement of cells, including fibroblasts and keratinocytes, to the wound site to facilitate tissue repair. This phase is marked by the formation of a provisional matrix that supports cell migration.

Next is the proliferative phase, where new tissues including collagen and extracellular matrix are produced, effectively filling in the wound and providing the necessary structural support.

Finally, the maturation phase occurs, which involves the remodeling of the tissue, leading to the development of scar tissue and restoring the strength and function of the skin. This phase can last for months or even years as the skin continues to adapt and refine the new tissue.

Each of these phases plays a distinct role, and the ordered progression through these stages is vital for effective wound healing.